A new saponin from tea seed pomace (Camellia oleifera Abel) and its protective effect on PC12 cells.

نویسندگان

  • Xin-Fu Zhang
  • Ying-Ying Han
  • Guan-Hu Bao
  • Tie-Jun Ling
  • Liang Zhang
  • Li-Ping Gao
  • Tao Xia
چکیده

A new triterpenoid saponin, oleiferasaponin A₁, was isolated from tea seed pomace (Camellia oleifera Abel). The structure of oleiferasaponin A₁ was elucidated on the basis of chemical and physicochemical evidence and was found to be 22-O-cis-2-hexenoyl-A₁-barrigenol 3-O-[β-D-galactopyranosyl(1→2)] [β-D-glucopyranosyl(1→2)-α-L-arabinopyranosyl(1→3)]-β-D-glucopyranosiduronic acid. PC12 cells injured with H₂O₂ were used as the model to test the protective effects of oleiferasaponin A₁. The results indicated that oleiferasaponin A₁ can potentially prevent the H₂O₂-induced cell death of PC12 cells.

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عنوان ژورنال:
  • Molecules

دوره 17 10  شماره 

صفحات  -

تاریخ انتشار 2012